What does PPMA mean in NEUROLOGY

Definition

PPMA is characterized by the gradual weakening and wasting of muscles, particularly those in the legs and arms. This muscle weakness can lead to difficulty with walking, balance, and other daily activities.

Causes

PPMA is thought to be caused by a combination of factors, including:

• Residual damage from the poliovirus: The poliovirus can cause permanent damage to motor neurons, the nerve cells that control muscle movement.
• Aging: With age, the remaining motor neurons may become less able to support muscle function.
• Immune system: The immune system may play a role in the development of PPMA.

Symptoms

Symptoms of PPMA can vary widely, but may include:

• Muscle weakness and wasting, especially in the legs and arms
• Fatigue
• Difficulty with walking and balance
• Tremors
• Muscle cramps

Diagnosis

Diagnosing PPMA can be challenging, as there is no specific test for the condition. Doctors will typically rely on a patient's history of poliovirus infection, a physical examination, and other tests to rule out other conditions.

Treatment

There is no cure for PPMA, but treatment can help manage symptoms and improve quality of life. Treatment may include:

• Physical therapy
• Occupational therapy
• Assistive devices, such as canes, walkers, or wheelchairs
• Medications to relieve muscle spasms or pain