What does PPMA mean in THERAPEUTICS
PPMA (Post-polio progressive muscular atrophy) is a late-onset neuromuscular disorder that affects individuals who have had polio in the past. It is characterized by progressive muscle weakness and atrophy, typically occurring decades after the initial polio infection.
PPMA meaning in Therapeutics in Medical
PPMA mostly used in an acronym Therapeutics in Category Medical that means Post-polio progressive muscular atrophy
Shorthand: PPMA,
Full Form: Post-polio progressive muscular atrophy
For more information of "Post-polio progressive muscular atrophy", see the section below.
» Medical » Therapeutics
Causes
PPMA is caused by the reactivation of dormant poliovirus particles that remain in the body after the acute polio infection. These reactivated viruses damage motor neurons, leading to muscle weakness and atrophy.
Symptoms
The symptoms of PPMA can vary in severity and progression rate. Common symptoms include:
- Progressive muscle weakness, particularly in the legs, arms, and trunk
- Muscle atrophy (wasting)
- Fatigue
- Difficulty breathing
- Speech and swallowing difficulties
- Pain
- Cold intolerance
Diagnosis
PPMA is diagnosed based on a combination of factors, including:
- Medical history of polio
- Physical examination
- Electromyography (EMG) to assess muscle function
- Nerve conduction studies
Treatment
There is no cure for PPMA, but treatment focuses on managing symptoms and improving quality of life. Treatment options may include:
- Physical therapy to strengthen muscles
- Occupational therapy to improve daily living skills
- Assistive devices (e.g., canes, wheelchairs)
- Medications to relieve pain and fatigue
Essential Questions and Answers on Post-polio progressive muscular atrophy in "MEDICAL»THERAPEUTICS"
What is post-polio progressive muscular atrophy (PPMA)?
Post-polio progressive muscular atrophy (PPMA) is a rare condition that can develop in people who have had polio in the past. It is characterized by a gradual weakening and wasting of muscles, typically in the legs, arms, or trunk.
What causes PPMA?
The exact cause of PPMA is unknown, but it is thought to be related to damage to the motor neurons (nerve cells that control muscle movement) that occurs during the initial polio infection. Over time, the damaged motor neurons may die, leading to muscle weakness and atrophy.
Who is at risk for PPMA?
Anyone who has had polio is at risk for PPMA, but it is most common in people who had polio as children. People who had more severe cases of polio or who had polio at a young age are at higher risk.
What are the symptoms of PPMA?
The symptoms of PPMA can vary depending on the individual, but they may include:
- Gradually worsening muscle weakness in the legs, arms, or trunk
- Muscle atrophy (wasting)
- Fatigue
- Difficulty breathing
- Difficulty swallowing
- Speech problems
How is PPMA diagnosed?
PPMA is diagnosed based on a person's history of polio, a physical examination, and tests such as:
- Electromyography (EMG): This test measures electrical activity in muscles to assess nerve damage.
- Nerve conduction studies: These tests measure how well nerves are conducting electrical signals.
- Muscle biopsy: This test involves taking a small sample of muscle tissue to examine under a microscope.
Is there a cure for PPMA?
There is currently no cure for PPMA, but there are treatments that can help to manage the symptoms and improve quality of life.
Final Words: PPMA is a challenging condition that can significantly impact an individual's life. However, with proper management and support, individuals with PPMA can live fulfilling and active lives.
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