What does AIA mean in BRITISH MEDICINE

Activation-induced apoptosis (AIA) is a form of programmed cell death that occurs in various organisms, particularly in certain types of immune cells. It is triggered by the activation of specific signaling pathways within the cell and can be initiated by a number of stimuli, including hormones and cytokines.

AIA occurs when a particular stimulus triggers an intracellular signal pathway, leading to changes in gene expression and triggering cell death pathways. In many cases, this involves the release of cytochrome c from mitochondria into the cytosol as well as other cellular events such as DNA damage or changes in membrane potentials.

AIA mainly affects certain types of immune cells, such as B lymphocytes and T lymphocytes. However, it has also been observed in other cell types such as cancer cells and neurons.

Possible triggers for AIA include hormones, cytokines, toxins or viruses. In addition, it can also be induced through exposure to radiation or certain drugs.

AIA helps an organism regulate its immune response by allowing it to remove unnecessary or “self” cells that could otherwise cause autoimmunity issues or interfere with an effective response to pathogens or tumors. Furthermore, it can also help to limit inflammation following an injury or infection. By using AIA as part of its defense against foreign entities such as viruses and bacteria, an organism effectively maintains immunological homeostasis.