What does CML mean in DISEASES
CML stands for Chronic Myeloid Leukemia, a type of cancer that affects the blood and bone marrow. It is a rare disease, accounting for about 15% of all leukemias. CML is characterized by an overproduction of white blood cells, specifically myeloid cells, which are normally responsible for fighting infections.
CML meaning in Diseases in Medical
CML mostly used in an acronym Diseases in Category Medical that means Chronic Myeloid Leukemia
Shorthand: CML,
Full Form: Chronic Myeloid Leukemia
For more information of "Chronic Myeloid Leukemia", see the section below.
What is CML?
CML is a chronic disease that typically progresses slowly. It is caused by a genetic abnormality called the Philadelphia chromosome, which is a fusion of two chromosomes, chromosomes 9 and 22. This abnormality leads to the production of an abnormal protein called the BCR-ABL protein, which promotes the uncontrolled growth of myeloid cells.
Symptoms of CML
- Fatigue
- Weakness
- Fever
- Night sweats
- Shortness of breath
- Easy bruising or bleeding
- Enlarged spleen
- Weight loss
Diagnosis of CML
CML is diagnosed through a combination of physical examination, blood tests, and bone marrow biopsy. Blood tests can detect high levels of white blood cells and the presence of the Philadelphia chromosome. A bone marrow biopsy can confirm the diagnosis and provide information about the stage of the disease.
Treatment of CML
Treatment for CML has improved significantly in recent years with the development of targeted therapies. The primary treatment option for CML is tyrosine kinase inhibitors (TKIs), which are drugs that block the activity of the BCR-ABL protein. TKIs have been shown to be highly effective in controlling CML and improving survival rates.
Essential Questions and Answers on Chronic Myeloid Leukemia in "MEDICAL»DISEASES"
What is Chronic Myeloid Leukemia (CML)?
CML is a type of cancer that starts in the blood-forming cells in the bone marrow. It is a chronic condition, meaning it can last for a long time. In CML, the bone marrow produces too many white blood cells, called myeloid cells. These abnormal cells can crowd out healthy blood cells, leading to anemia, infection, and other health problems.
What causes CML?
CML is caused by a genetic mutation that creates a fusion gene called BCR-ABL. This gene causes the bone marrow to produce abnormal myeloid cells. The exact cause of the mutation is unknown, but it is not inherited.
What are the symptoms of CML?
In the early stages, CML may not cause any noticeable symptoms. As the condition progresses, symptoms may include:
- Fatigue
- Weakness
- Shortness of breath
- Easy bruising or bleeding
- Frequent infections
- Bone pain
- Swollen abdomen or spleen
How is CML diagnosed?
CML is diagnosed with a blood test that looks for the BCR-ABL fusion gene. A bone marrow biopsy may also be done to confirm the diagnosis and evaluate the extent of the disease.
What are the treatment options for CML?
Treatment for CML has advanced significantly in recent years. The goal of treatment is to control the disease and improve quality of life. Treatment options may include:
- Tyrosine kinase inhibitors (TKIs): These are targeted therapies that block the BCR-ABL fusion gene. TKIs have significantly improved the prognosis of CML patients.
- Stem cell transplant: This procedure involves replacing the patient's bone marrow with healthy stem cells from a donor.
What is the prognosis for CML?
With early diagnosis and proper treatment, most patients with CML can live long, healthy lives. However, the prognosis can vary depending on the stage of the disease and the patient's overall health.
Final Words: CML is a serious but manageable disease. With early diagnosis and appropriate treatment, patients can achieve long-term remission and a good quality of life. Advances in targeted therapies have revolutionized the treatment of CML, offering patients hope for a positive outcome.
CML also stands for: |
|
| All stands for CML |