What does PSAA mean in UNCLASSIFIED
PSAA stands for Pneumococcal Surface Adhesin A. It is a protein expressed on the surface of the bacterium Streptococcus pneumoniae, also known as the pneumococcus.
PSAA meaning in Unclassified in Miscellaneous
PSAA mostly used in an acronym Unclassified in Category Miscellaneous that means Pneumococcal surface adhesin A
Shorthand: PSAA,
Full Form: Pneumococcal surface adhesin A
For more information of "Pneumococcal surface adhesin A", see the section below.
Meaning of PSAA
PSAA is a virulence factor that plays a crucial role in the pathogenesis of pneumococcal infections. It mediates the adherence of the bacteria to host cells, allowing them to colonize and invade the respiratory tract.
Function of PSAA
- Adhesion to host cells: PSAA binds to a specific receptor on the surface of human respiratory epithelial cells called the sialic acid-containing glycoproteins. This interaction enables the bacteria to adhere tightly to the host cell and initiate infection.
- Biofilm formation: PSAA also promotes the formation of bacterial biofilms, which are protective communities of bacteria that are resistant to antimicrobial agents.
- Immune evasion: PSAA has been shown to interfere with the host immune response by inhibiting phagocytosis and complement-mediated killing.
Importance of PSAA
PSAA is a major virulence factor in pneumococcal infections. It contributes to the initiation, colonization, and persistence of the bacteria in the host. Understanding the role of PSAA is essential for developing effective prevention and treatment strategies for pneumococcal diseases.
Essential Questions and Answers on Pneumococcal surface adhesin A in "MISCELLANEOUS»UNFILED"
What is Pneumococcal surface adhesin A (PSAA)?
Pneumococcal surface adhesin A (PSAA) is a protein found on the surface of the bacterium Streptococcus pneumoniae, commonly known as the pneumococcus. It is a virulence factor that plays a crucial role in the bacterium's ability to cause infections. PSAA binds to specific receptors on human respiratory epithelial cells, facilitating the initial attachment and colonization of the bacterium in the respiratory tract.
Final Words: PSAA is a crucial surface protein of Streptococcus pneumoniae that plays a significant role in the development of pneumococcal infections. It mediates bacterial adherence, biofilm formation, and immune evasion. Targeting PSAA is a promising approach for the development of novel antimicrobial therapies and vaccines against pneumococcal diseases.
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