What does AL mean in PHYSIOLOGY
AL stands for Artemether-lumefantrin, a combination antimalarial medication used to treat uncomplicated and severe malaria caused by Plasmodium falciparum, a type of malaria parasite. It is a fixed-dose combination of two antimalarial drugs: Artemether (an artemisinin derivative) and lumefantrine.
AL meaning in Physiology in Medical
AL mostly used in an acronym Physiology in Category Medical that means Artemether-lumefantrin
Shorthand: AL,
Full Form: Artemether-lumefantrin
For more information of "Artemether-lumefantrin", see the section below.
» Medical » Physiology
What does AL Stand for?
- A - Artemether
- L - Lumefantrine
AL Mechanism of Action
Artemether rapidly kills the malaria parasite during the early ring stage of its life cycle. Lumefantrine acts as a blood schizonticide, eliminating the parasite during the later stages of its life cycle.
AL Effectiveness
AL is highly effective in treating uncomplicated and severe malaria. It has been shown to have a cure rate of over 95% in uncomplicated malaria.
AL Dosage and Administration
AL is taken orally, once daily for 3 days. The recommended dosage is based on body weight.
AL Side Effects
The most common side effects of AL include:
- Nausea
- Vomiting
- Abdominal pain
- Headache
- Weakness
- Dizziness
AL Contraindications
AL is contraindicated in patients with:
- Known hypersensitivity to artemether or lumefantrine
- Severe liver impairment
Essential Questions and Answers on Artemether-lumefantrin in "MEDICAL»PHYSIOLOGY"
What is Artemether-lumefantrin (AL)?
AL is a medication combination containing artemether and lumefantrin, used to treat uncomplicated malaria in adults and children weighing 5 kg or more. It is a first-line treatment for malaria in many countries.
How does AL work?
Artemether and lumefantrin work together to kill the malaria parasite. Artemether rapidly kills the parasite in the blood, while lumefantrin prevents the parasite from maturing and reproducing in the liver.
What is the recommended dosage of AL?
The dosage of AL depends on the patient's weight and is typically given as a 6-dose regimen over 3 days. It is important to take the medication exactly as prescribed to ensure its effectiveness.
What are the potential side effects of AL?
Common side effects of AL include nausea, vomiting, abdominal pain, and dizziness. More serious side effects, such as liver problems, are rare.
Who should not take AL?
AL is not recommended for people with known allergies to artemether or lumefantrin, or for pregnant women.
What should I do if I miss a dose of AL?
If a dose of AL is missed, it should be taken as soon as possible. However, if it is close to the time for the next dose, the missed dose should be skipped.
What is the cure rate of AL for malaria?
AL has a high cure rate for uncomplicated malaria, typically around 95-100%.
Is AL available as a generic medication?
Yes, generic versions of AL are available, which are equivalent to the brand-name medication in terms of effectiveness and safety.
How should AL be stored?
AL should be stored at room temperature (15-25°C) and protected from light.
Final Words: AL (Artemether-lumefantrin) is a highly effective combination antimalarial medication used to treat uncomplicated and severe malaria caused by Plasmodium falciparum. It is generally well-tolerated, with common side effects being mild and transient. However, it is important to follow the prescribed dosage and administration guidelines to ensure optimal efficacy and minimize the risk of side effects.
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