What does UTR mean in HUMAN GENOME
UTR stands for untranslated region, a section of a gene which does not code for proteins. UTRs are parts of the DNA strand found outside of (5' and 3') the coding region, or exon, of a gene. Located on either side of the exons, they help regulate gene expression but do not form part of the resulting protein or polypeptide sequence.
UTR meaning in Human Genome in Medical
UTR mostly used in an acronym Human Genome in Category Medical that means untranslated region
Shorthand: UTR,
Full Form: untranslated region
For more information of "untranslated region", see the section below.
» Medical » Human Genome
What Is the Difference Between 5'UTRs & 3'UTRs ? The primary difference between 5'UTRs and 3'UTRs is their location within mRNA molecules
5'UTRs occur at the beginning (5') end while 3'UTRs occur at their end (3'). The secondary difference is that while 5'UTRs can contain regulatory sequences such as ribosome binding sites which control translation initiation, 3’UTRs tend to play a greater role in mRNA stability due to containing sequences known as AU-rich elements which increase transcript degradation rates when bound by specific proteins.
Essential Questions and Answers on untranslated region in "MEDICAL»GENOME"
What is an UTR?
UTR stands for Unranslated Region. It is a region of non-coding DNA or mRNA, usually located at the ends of genes, which does not have an effect on translation. UTRs are found in both Eukaryotes and Prokaryotes and act as regulatory elements in gene expression.
How does UTR regulate gene expression?
UTRs regulate gene expression by controlling transcription rate and mRNA stability. The size and sequence of the UTR can influence how quickly a gene is transcribed into mRNA, as well as how long that mRNA remains stable and available for translation into proteins.
What types of elements are found in UTR?
In a typical cell, UTRs contain enhancer or silencer elements such as polyadenylation signal sequences, transcription factor binding sites, microRNA binding sites, ribosomal binding sites and other regulatory elements.
Are all genes affected by UTRs?
Not all genes have an associated UTR, but many do. It is estimated that about 50% of human protein-coding genes have at least one untranslated region associated with them.
Does the size of an organism's genome affect its number of UTRs?
Yes, the size of an organism’s genome can affect their number of UTRs as larger genomes generally contain more regions associated with gene regulation. For instance, animals tend to have more complex genomes than plants which can be reflected in their greater number of UTRs per gene compared to plants.
How can you identify a gene’s untranslated regions?
To identify a gene’s untranslated region (UTR), one needs to use bioinformatics tools such as NCBI's BLAST program or other sequence comparison programs to search through databases for similar sequences to find potentially related RNAs or DNAs that may function similarly within organisms. Additionally one could use annotation tools like GFF or GTF files that mark specific regions on a genome for further analysis regarding their role in regulating gene expression.
Final Words:
In conclusion, UTRs play an indispensable role in regulating gene expression by attaching regulatory proteins to RNA transcripts thus modulating their life span and control post-transcriptional processing activities such as mRNA stability and transportion into cytosol. As such, understanding how these regions work is key to unlocking our full genetic potential.
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