What does TSG mean in ONCOLOGY
Tumor suppressor genes (TSGs) are a class of genes that, when mutated, can lead to uncontrolled cell growth and cancer. TSGs act as a type of molecular brake on uncontrolled cell division. When TSGs are not functioning correctly, this regulatory system breaks down and the cells divide uncontrollably leading to tumor formation.
TSG meaning in Oncology in Medical
TSG mostly used in an acronym Oncology in Category Medical that means Tumor Suppressor Gene
Shorthand: TSG,
Full Form: Tumor Suppressor Gene
For more information of "Tumor Suppressor Gene", see the section below.
Essential Questions and Answers on Tumor Suppressor Gene in "MEDICAL»ONCOLOGY"
What is a Tumor Suppressor Gene?
A tumor suppressor gene (TSG) is a type of gene that helps regulate cell growth and division. When mutated or inactivated, TSGs can lead to uncontrolled growth and the formation of tumors.
How does a Tumor Suppressor Gene work?
Tumor suppressor genes act as molecular brakes on uncontrolled cell division. When these molecules are functioning normally, the regulatory system remains intact, preventing the cells from dividing unchecked which could potentially lead to tumours.
What happens when a Tumor Suppressor Gene is mutated?
Mutations in tumor suppressor genes can cause the regulatory system to break down and result in cell division that is uncontrolled - leading to tumor formations.
Are there different kinds of Tumor Suppressor Genes?
Yes, there are many different types of tumor suppressors including p53, RB1, APC, PTEN and STK11 among others. Each has specific functions related to controlling cell growth which can be disrupted if they are mutated or inactivated.
What disorder are caused by mutations in Tumor Suppressor Genes?
Mutations in tumor suppressors can lead to various disorders such as cancers like liver cancer or colon cancer as well as other conditions like Cowden syndrome or Li-Fraumeni Syndrome.
Final Words:
In summary, Tumor Suppressor Genes (TSGs) play an important role in regulating cell growth and tumors formation when they are functioning properly but when mutated or deactivated this control mechanism breaks down resulting in unchecked cell growth leading to tumors forms.
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