What does TKM mean in TORONTO STOCK EXCHANGE
TKM stands for Tekmira Pharmaceuticals Corporation. It is a biopharmaceutical company located in Burnaby, British Columbia, Canada. The company specializes in the development of RNA interference (RNAi) therapeutics for serious and life-threatening rare diseases and conditions.
TKM meaning in Toronto Stock Exchange in Business
TKM mostly used in an acronym Toronto Stock Exchange in Category Business that means Tekmira Pharmaceuticals Corporation
Shorthand: TKM,
Full Form: Tekmira Pharmaceuticals Corporation
For more information of "Tekmira Pharmaceuticals Corporation", see the section below.
Essential Questions and Answers on Tekmira Pharmaceuticals Corporation in "BUSINESS»TSX"
What exactly is RNAi and what does it do?
RNA interference (RNAi) is a process by which genetic material, such as DNA or RNA, can be silenced or “turned off†to prevent its expression or activity. This means that when RNAi is used in therapeutic applications, the affected gene's protein product cannot be produced and therefore cannot perform its normal function or cause disease.
What diseases does Tekmira target with its treatments?
Tekmira primarily focuses on developing treatments for difficult-to-treat rare diseases and conditions such as hemophilia A and B, alpha-1 antitrypsin deficiency (AATD), cystic fibrosis and other genetic disorders.
How does Tekmira develop these treatments?
Tekmira utilizes its proprietary lipid nanoparticle (LNP) delivery technology to formulate therapeutic candidates targeting underlying disease mechanisms with the potential of improved safety profiles compared to existing therapies.
Has Tekmira had any success?
Yes! In 2016, the U.S. Food & Drug Administration (FDA) approved an LNP formulation developed by Tekmira known as Onpattroâ„¢ for the treatment of peripheral nerve disease caused by hereditary transthyretin (hATTR).
What are some advantages of using an LNP formulation instead of other treatments?
An advantage of using an LNP formulation is that it enables long-term release of large doses of mRNA without triggering an immune response from the body's natural defense mechanisms—which can help optimize efficacy while reducing side effects associated with conventional intravenous drugs used to treat diseases like hATTR amyloidosis.
Final Words:
Through its expertise in developing lipid nanoparticle formulations and innovative approach to drug delivery technology, Tekmira Pharmaceuticals Corporation has been able to successfully develop treatments for a range of rare conditions and have them approved by the FDA with great success.
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