What does TFO mean in HUMAN GENOME
A Triplex Forming Oligonucleotide (TFO) is a short, single-stranded DNA molecule designed to bind to a targeted double-stranded DNA sequence through the formation of a three-strand hybrid genomic structure. It is an important tool used in DNA engineering and research.
TFO meaning in Human Genome in Medical
TFO mostly used in an acronym Human Genome in Category Medical that means Triplex Forming Oligonucleotide
Shorthand: TFO,
Full Form: Triplex Forming Oligonucleotide
For more information of "Triplex Forming Oligonucleotide", see the section below.
» Medical » Human Genome
Essential Questions and Answers on Triplex Forming Oligonucleotide in "MEDICAL»GENOME"
What is a TFO?
A TFO is a short, single-stranded DNA molecule designed to bind to a targeted double-stranded DNA sequence through the formation of a three-strand hybrid genomic structure.
How does a TFO work?
The TFO binds specifically to its target sequence by forming hydrogen bonds between complementary base pairs on the single strand with the target sequence. This forms an intramolecular triplex nucleic acid, which makes possible precise gene targeting without side effects.
What are some uses for a TFO?
TFOs are used in many applications including epigenetic regulation, gene therapy, target amplification and sequencing, and drug development. They can also be used as tools for therapeutic expression modulation or precise genome editing with CRISPR/Cas systems.
Final Words:
TFOs are powerful tools for precise gene targeting and manipulation that have multiple potential applications in biotechnology and medical research.
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