What does PTPB mean in HUMAN GENOME

PTPB stands for Protein Tyrosine Phosphatase - Beta, which is an important enzyme involved in regulating cell signaling.

PTPB functions by dephosphorylating tyrosine residues of proteins and playing a role in the regulation of various cellular processes such as cell growth, differentiation, and survival.

PTPB interacts with proteins containing tyrosine residues for its effector actions on cells.

The roles of PTPB include modulation of metabolic pathways, maintenance of cellular homeostasis, control over apoptosis and autophagy, regulation of gene expression, coordination between different receptors in cells and many other post-translational modifications.

Mutations in the gene encoding for PTPB can lead to several diseases including dilated cardiomyopathy, idiopathic pulmonary fibrosis and hereditary sensorimotor neuropathy.