What does PEMC mean in HUMAN GENOME

Characteristics

PEMCs have a high degree of plasticity, meaning they can differentiate into many different lineages, including those involving components of muscle tissue such as myoblasts, fibroblasts and vascular endothelial cells. These cells also possess immunomodulatory properties which help regulate inflammation and immune responses. Moreover, they can be easily isolated and cultured in vitro, making them suitable for research purposes.

Applications

The wide range of features displayed by PEMCs allows them to be used for various medical and scientific applications. For example, studies have demonstrated that these cells can induce regeneration of damaged heart tissue after a heart attack or other cardiac event. Additionally, animal studies suggest that transplantation of PEMC-derived myoblast sheets might be useful for improving muscular function in cases of severe muscular dystrophy or other conditions causing muscle wasting. Furthermore, due to their potency as both progenitors and regulators of the immune system, PEMCs are being investigated to determine whether they may provide therapeutic benefit in diseases with autoimmune components such as multiple sclerosis or rheumatoid arthritis.