What does OTOG mean in UNCLASSIFIED
OTOG is an abbreviation for the Otogelin gene, which is a member of the heterotrimeric guanine nucleotide-binding protein (G protein) family. This gene acts as a molecular switch and functions in signal transduction pathways in response to various cell stimuli. The activity of this gene has been associated with many diseases such as Parkinson’s disease, pain and inflammatory bowel disease, among others. OTOG stands for ‘Otogelin’, which is the name of the gene product itself. This abbreviation is used widely within the scientific community to refer to the gene product and its functions.
OTOG meaning in Unclassified in Miscellaneous
OTOG mostly used in an acronym Unclassified in Category Miscellaneous that means of the otogelin gene
Shorthand: OTOG,
Full Form: of the otogelin gene
For more information of "of the otogelin gene", see the section below.
OTOG Meaning
OTOG stands for Otogelin, a G protein-coupled receptor (GPCR) that is expressed at low levels in peripheral tissues including skin, lung, liver, spleen, lymph nodes and brain. OTOG plays a crucial role in signal transduction pathways by activating or inhibiting other proteins within the pathway upon stimulation from various agonists. It has mainly been studied for its involvement in pain perception and inflammation processes due to its expression in cells found throughout these pathways.
OTOG Full Form
The full form of OTOG is Otogelin, where ‘Otog’ comes from the Greek word meaning ear – which refers to the cellular location where it was first discovered - and 'lin' stands for lineage or related family members. OTOG was initially identified through its similarity to other GPCRs involved in pain sensation but further research has since revealed roles for it in multiple processes such as cell adhesion and complement activation.
Essential Questions and Answers on of the otogelin gene in "MISCELLANEOUS»UNFILED"
What is the Otogelin Gene?
The otogelin gene, also known as OTOG, encodes a small membrane-associated protein involved in the formation of hair cell stereocilia. It is found in the inner ear and plays an essential role in hearing.
Where is the Otogelin Gene Located?
The gene encoding OTOG is located on chromosome 11 in humans. It resides in the inner ear epithelial cells, and is responsible for controlling specific aspects of hair cell development.
What does the Otogelin Gene Do?
OTOG helps to regulate important cellular processes involved with developing hair cells inside of the inner ear. Specifically, it helps to promote hair bundle fomentation, which is important for auditory function.
How Does the Otogelin Gene Affect Hearing?
The otogelin gene plays a role in regulating certain aspects of auditory development including hair bundle formation and organization within the inner ear. By doing so, it helps to ensure normal hearing functions occur correctly.
Why Is Otogein Important For Hearing?
Without proper functioning of the otogein gene, various aspects of auditory development may be impaired leading to hearing loss or other auditory problems. Therefore, it is important for maintaining normal hearing function.
Are There Any Disorders Linked To The Otogein Gene?
Yes - mutations in OTOG may lead to Usher syndrome type IH (USH1H), an autosomal recessive disorder characterized by profound congenital sensorineural deafness with vestibular impairment and progressive vision loss due to retinal degeneration.
Final Words:
In conclusion, OTOG stands for Otogelin - a G protein-coupled receptor that is embroiled in numerous cellular processes ranging from pain perception to complement activation. It is located near auditory receptors which gave it its name; however researchers have since discovered much more about its function beyond just auditory responses. Understanding OTOG's role may lead us closer to understanding how many diseases progress on a molecular level.