What does MDLH mean in UNCLASSIFIED
MDLH stands for mitochondrial DNA lacking HepG2, which is a cell line derived from the human hepatocellular carcinoma cell line. It lacks mitochondrial DNA due to a spontaneous deletion of the mitochondrial genome. This makes it useful for studies involving human cells and gene expression in vitro.
MDLH meaning in Unclassified in Miscellaneous
MDLH mostly used in an acronym Unclassified in Category Miscellaneous that means mitochondrial DNA lacking HepG2
Shorthand: MDLH,
Full Form: mitochondrial DNA lacking HepG2
For more information of "mitochondrial DNA lacking HepG2", see the section below.
Essential Questions and Answers on mitochondrial DNA lacking HepG2 in "MISCELLANEOUS»UNFILED"
What is the purpose of MDLH?
The purpose of MDLH is to provide a cell line for studying human genes and gene expression without having to be concerned about factors associated with mitochondrial DNA.
What does MDLH stand for?
MDLH stands for Mitochondrial DNA Lacking HepG2.
Can the mitochondria be introduced back into the cells?
Yes, it is possible to re-introduce mitochondria into the cells. Studies use different strategies such as using viral vectors or introduction of compensatory mutations in order to restore normal respiratory chain activity.
How will this help in studying respiration and metabolism?
Having a lack of mitochondrial DNA in the cells will allow researchers to see how cellular respiration and metabolism are affected when there are no mitochondria present, providing valuable insight on these topics.
What type of cell line is used for this study?
The cell line used for this study is derived from human hepatocellular carcinoma cells.
Final Words:
MDLH stands for Mitochondrial DNA Lacking HepG2 and provides an invaluable tool for studying gene expression and cellular respiration without having to worry about factors associated with mitochondrial genetics as they have been removed from the cell line. This can be extremely beneficial in understanding how respiration and metabolism works without being hindered by any factors related to mitochondrial genetics.