What does LWD mean in PHYSIOLOGY
Leri-Weill Dischondrosteosis (LWD) is a rare genetic skeletal disorder that affects the development and function of bones. It is inherited in an autosomal dominant pattern, meaning that only one parent needs to have the gene mutation for their child to inherit it. People with LWD have short stature, deformities of the forearm and wrist, and a distinctive facial appearance.
LWD meaning in Physiology in Medical
LWD mostly used in an acronym Physiology in Category Medical that means Leri-Weill Dischondrosteosis
Shorthand: LWD,
Full Form: Leri-Weill Dischondrosteosis
For more information of "Leri-Weill Dischondrosteosis", see the section below.
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Essential Questions and Answers on Leri-Weill Dischondrosteosis in "MEDICAL»PHYSIOLOGY"
What causes Leri-Weill Dischondrosteosis?
LWD is caused by a mutation in the SHOX gene which affects bone formation and growth. This mutation can be inherited from a parent who has it or arise spontaneously in an individual with no family history of the disorder.
How common is Leri-Weill Dischondrosteosis?
The prevalence of LWD is unknown but considered to be rare. Estimates suggest that between 1 in 20,000 and 1 in 100,000 people are affected by this disorder.
What are some signs and symptoms of Leri-Weill Dischondrosteosis?
Signs and symptoms include short stature, reduced arm span, bone deformities such as Madelung deformity of the radial head/neck, cubitus valgus or curved elbows inwardly towards each other, shortening of ulna bones and malformation at wrist joint level with limited movement capabilities. Facial features may also include hypertelorism (wide-set eyes), proptosis (bulging eyes), retrognathia (receding chin), low set ears among others.
Is there a cure for Leri-Weill Dischondrosteosis?
There is currently no cure for LWD; however therapies such as physical therapy or surgery may be used to help manage limb deformities associated with this condition. Specialized shoes may also help individuals walk better if they experience difficulties due to bone malformations in feet or ankles.
What complications can occur due to Leri-Weill Discondrosteosis?
Complications can include complications due to skeletal deformities such as impaired movement range in arms/wrists, hearing loss due to otitis media caused by Eustachian tube dysfunction related to airway obstruction from anomalies due to facial characteristics associated with LWD, scoliosis due to spine abnormalities and joint dislocation during childhood growth spurts.
Final Words:
Leri-Weill Dischonstrosteosis is a rare genetic skeletal disorder that can result in significant limitations affecting daily life activities for those affected. While there may not yet be a cure for LWD treatment options exist that can offer symptom relief and help improve functioning levels.
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