What does AANCA mean in UNCLASSIFIED
Atypical anti-neutrophil cytoplasmic antibodies (AANCA) are a group of autoantibodies directed against antigens located in the cytoplasm of neutrophils. These antibodies have been identified as a potential cause of several autoimmune diseases such as systemic lupus erythematosus, rheumatoid arthritis, inflammatory bowel disease and other autoimmune disorders. AANCA testing is used to help diagnose and monitor these conditions.
AANCA meaning in Unclassified in Miscellaneous
AANCA mostly used in an acronym Unclassified in Category Miscellaneous that means Atypical Anti Neutrophil Cytoplasmic Antigens
Shorthand: AANCA,
Full Form: Atypical Anti Neutrophil Cytoplasmic Antigens
For more information of "Atypical Anti Neutrophil Cytoplasmic Antigens", see the section below.
Essential Questions and Answers on Atypical Anti Neutrophil Cytoplasmic Antigens in "MISCELLANEOUS»UNFILED"
What is AANCA?
AANCA stands for Atypical Anti Neutrophil Cytoplasmic Antigens. It's a group of autoantibodies that are found in some types of inflammatory conditions, such as vasculitis.
What is the role of AANCA in vasculitis?
The presence of AANCA in the blood can be used to diagnose vasculitis and to help identify which type of vasculitis individuals may have.
How is AANCA tested?
AANCA is typically tested by an immunofluorescence assay (IFA) or an enzyme-linked immunosorbent assay (ELISA). These tests detect substances called antineutrophil cytoplasmic antibodies (ANCAs) against certain proteins found inside neutrophils, a type of white blood cell.
Does everyone with vasculitis have positive AANCA test results?
Not necessarily. While 90% of people with Wegener's granulomatosis and 60% to 70% of those with microscopic polyangiitis will have positive ANCA test results, not all cases will show a positive result.
Can other conditions produce a positive ANCA result?
Yes, several other diseases can cause false-positive ANCA results including bacterial infections, drugs such as antibiotics, autoimmune conditions like lupus or rheumatoid arthritis, connective tissue disorders and thromboembolic diseases like deep vein thrombosis or pulmonary embolism.
What do abnormal ANCA test results mean?
Abnormal ANCA test results can indicate the presence of an underlying condition like vasculitis or another immune-mediated disease that would need further investigation and treatment from your healthcare provider.
Are there any risks associated with having the ANCA test done?
There are no serious risks associated with having the ANCA test done as it involves having a routine blood sample taken from your arm using a needle and syringe at your doctor's office or laboratory.
What follow-up care is necessary if my ANCA test comes back abnormal?
If your ANCA test comes back abnormal you should make an appointment with your healthcare provider to discuss further evaluation steps and any treatment options that may be available for the underlying condition identified by the diagnostic tests.
How long does it take to receive results for the ANCA Test?
The time it takes to get your results varies depending on the lab but typically they should receive them within 1-2 weeks after the sample has been collected.
Final Words:
Atypical Anti-Neutrophil Cytoplasmic Antigen (AANCA) testing can help healthcare professionals diagnose or monitor patients with certain autoimmune illnesses such as SLE, RA, IBD and more. This test detects autoantibodies targeting antigens located within the cytoplasm of neutrophils to help healthcare providers better manage these conditions and provide optimized care for their patients.