What does HDLP mean in UNCLASSIFIED
HDLP stands for Histone Deacetylase Like Protein. It is a kind of protein which is structurally related to histone deacetylases, but lacking their enzymatic activity. HDLPs regulate gene expression during development and cell division, acting as transcriptional regulators. HDLP interacts with other proteins, DNA-binding proteins and ligands to modify gene expression processes in eukaryotic cells. They are involved in the epigenetic regulation of chromatin remodelling and cell differentiation.
HDLP meaning in Unclassified in Miscellaneous
HDLP mostly used in an acronym Unclassified in Category Miscellaneous that means Histone deacetylase like protein
Shorthand: HDLP,
Full Form: Histone deacetylase like protein
For more information of "Histone deacetylase like protein", see the section below.
Definition
Histone Deacetylase Like Proteins (HDLPs) are proteins that share structural similarities with histone deacetylases (HDACs). However, while HDACs have the core enzyme activity of catalyzing the hydrolysis of acetyl-lysine residues on histones and non-histones substrates, HDLPs do not possess this ability. Instead they form associated complexes with other proteins and DNA binding motifs to modulate various processes such as cell growth, apoptosis, inflammation and cancer progression via epigenetic regulation of chromatin remodeling. Function: HDLP functions by interacting with other proteins like transcription factors or ligands to modify gene expression processes in the eukaryotic cells. Through these interactions they can influence several molecular pathways including those involved in stem cell differentiation, tissue development, metabolism regulation and inflammation modulation among others. The interaction between HDLPs and HDACs has been shown to increase transcriptional repressions or decrease transcriptional activations via histone modification or inhibition of transcription factor accessibility at promoter regions respectively. Furthermore they may also interact directly with DNA structures such as nucleosomes. Thus, overall HDLPs play a crucial role in controlling some cell processes by modulating gene expression levels through different mechanisms such as epigenetic remodeling.
Final Words:
In conclusion, Histone Deacetylase Like Proteins (HDLPs) are regulatory molecules that help control cellular activities through interactions with mRNA coding sequences or chromatin structures like nucleosomes resulting in changes in gene expression levels which can affect multiple cellular pathways including replication rate, stem cell differentiation among several others. As a result HDLP plays an important role when it comes to understanding how genes are regulated during development and how misregulation leads to various diseases like cancer.