What does HCMI mean in CANCER
The Human Cancer Models Initiative (HCMI) is an international public–private consortium that works to accelerate the development of new treatments for cancer by developing models of human cancer cells in mice. The HCMI was founded by a group of leading companies and organizations dedicated to advancing research and development in the areas of oncology, cell biology, stem cell technology, genomics, and immunotherapy. Its mission is to create engineered human cancer mouse models that accurately reflect the diversity of human cancers and can be used to validate novel therapies. By providing access to these novel tools, HCMI provides a platform for scientists and drug developers to rapidly advance progress in cancer research and therapeutics.
HCMI meaning in Cancer in Medical
HCMI mostly used in an acronym Cancer in Category Medical that means Human Cancer Models Initiative
Shorthand: HCMI,
Full Form: Human Cancer Models Initiative
For more information of "Human Cancer Models Initiative", see the section below.
Essential Questions and Answers on Human Cancer Models Initiative in "MEDICAL»CANCER"
What is the Human Cancer Models Initiative (HCMI)?
The Human Cancer Models Initiative (HCMI) is a public-private partnership launched by the National Cancer Institute (NCI) and funded in part by several biopharmaceutical companies. HCMI seeks to develop human cancer models using a variety of technologies and to make them available for research. The goal of HCMI is to provide more accurate models of human cancers that will enable researchers to better study the biology, genetics, and progression of cancer and to speed up new treatments for patients.
What types of cancer are studied in HCMI?
HCMI studies many different types of cancer including breast, lung, prostate, colon, skin, head and neck, ovarian, pancreatic and other rare cancers.
What types of technology are used in HCMI?
Technology used in HCMI includes 3D organoid cultures to model tumor microenvironment interactions; patient-derived xenografts for advanced mouse modeling; genomic analysis; and gene engineering tools such as CRISPR/Cas9.
How does HCMI help progress cancer research?
By developing better models for studying the biology of cancer and its progression using relevant technology such as 3D organoid cultures or patient-derived xenografts, researchers can learn more about how different cancers function which can then be used to speed up the development of new treatments that are tailored specifically for those individual cancers.
Who funds HCMI?
The National Cancer Institute (NCI) is a major funder of HCMI along with several biopharmaceutical companies such as Merck & Co., Novartis AG., Pfizer Inc., AstraZeneca PLC., Takeda Pharmaceutical Company Ltd., Eli Lilly and Company, Genentech/Roche Group, Bristol-Myers Squibb Company, GlaxoSmithKline PLC., Celgene Corporation and Regeneron Pharmaceuticals Inc.
How do I access research made possible through HCMI initiatives?
All data generated from research conducted through the Human Cancer Model Initiative will be available via NCI's Genomic Data Commons (GDC). Researchers wishing to use this data should register with GDC at https://portal.gdc.cancer.gov/. The data can also be accessed via dbGaP at https://www.ncbi.nlm.nih.gov/gap/.
Where can I find publications related to research conducted through the Human Cancer Model Initiative?
A searchable database containing publications related to research conducted through the Human Cancer Model initiative can be found on PubMed at https://www.ncbi.nlm.nih.gov/pubmed/?term=human+cancer+models+initiative+.
Final Words:
The Human Cancer Models Initiative (HCMI) is a multi-institutional effort dedicated to accelerating research and development in oncology through the use of engineered mouse models created from human-derived cancer cells. By providing access to reliable preclinical tools, this initiative enables comprehensive discovery efforts so scientists can develop effective treatments with greater speed and accuracy than ever before.
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