What does ACST mean in SURGICAL
The ACST, or Asymptomatic Carotid Surgery Trial, is a trial that was conducted in the 1990s to evaluate the effect of surgical intervention on stroke risk in patients with asymptomatic carotid stenosis. The study involved over 2,000 participants from eight countries, including the United States, Canada, and the United Kingdom. The trial evaluated whether carotid endarterectomy (surgical removal of plaque) and medical management alone were effective in reducing strokes resulting from carotid artery occlusions. The data from this trial demonstrated that surgery reduced stroke risk by 64%, significantly more than medical management alone. This information has been invaluable for informing clinical guidelines for asymptomatic carotid stenosis patients ever since it was presented in 1998.
ACST meaning in Surgical in Medical
ACST mostly used in an acronym Surgical in Category Medical that means Asymptomatic Carotid Surgery Trial
Shorthand: ACST,
Full Form: Asymptomatic Carotid Surgery Trial
For more information of "Asymptomatic Carotid Surgery Trial", see the section below.
Meaning
ACST stands for Asymptomatic Carotid Surgery Trial and is used to refer to the large scale clinical study conducted between 1993 and 1998 that examined the efficacy of carotid endarterectomy (surgical removal of plaque) compared to medical management alone in reducing stroke risk among those with asymptomatic carotid artery occlusions. Data obtained from this trial indicated that surgery reduced stroke risk by 64%, an incredibly significant difference when compared to medical management alone.
Essential Questions and Answers on Asymptomatic Carotid Surgery Trial in "MEDICAL»SURGICAL"
What is the Asymptomatic Carotid Surgery Trial?
The Asymptomatic Carotid Surgery Trial (ACST) was a large-scale randomized controlled clinical trial designed to assess whether carotid artery surgery reduces the risk of stroke in patients with asymptomatic carotid stenosis.
Who is eligible for ACST?
Eligibility criteria included males and females aged at least 40 years who had significant (>50%) asymptomatic carotid artery stenosis determined by Doppler ultrasonography or arteriography.
How long did the ACST trial run for?
The ACST trial began in August 1996 and ended in December 2003.
What types of treatments were used for ACST?
The treatments used in this trial included either carotid endarterectomy or carotid stenting.
Was follow-up care provided during ACST?
Yes, all participants were monitored closely over 5 years to assess their cardiovascular health and identify any subsequent strokes.
Were any preoperative imaging tests performed during ACST?
Participants had assessments including duplex ultrasound, computed tomography, magnetic resonance imaging, or angiograms preoperatively before they received treatment.
What safety precautions were taken during ACST?
Patients were closely monitored during surgery and followed up regularly afterwards with neurological examinations and ultrasounds to detect any stroke events which may have occurred due to surgery or other factors. Additionally, safety measures such as antithrombotic medications were prescribed depending on individual risk factors.
How was data collected during ACST?
Data regarding participant baseline characteristics, outcomes, and follow-up information was collected prospectively at each visit throughout the 5-year study period. Additionally, data was supplemented from ancillary studies such as neurocognitive testing to improve accuracy and validity of results.
Final Words:
The Asymptomatic Carotid Surgery Trial has contributed immensely to our understanding of how we can better manage those who have an asymptomatic condition known as carotid artery occlusion - a narrowing or blockage in one or both of these arteries which could lead to a stroke if left untreated. By comparing surgical intervention against medical management, we now have clear evidence that surgical intervention is more effective at reducing stroke risk in those with asymptomatic conditions of this nature.
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