What does ACIS mean in SYNDROMES
Acquired Cellular Induration Syndrome (ACIS) is a rare form of lymphoproliferative disorder that causes the overgrowth of normal cells and tissues, leading to thickening of the affected areas. It can affect any area of the body, with symptoms depending on where it is located. ACIS is most often found in the skin and blood vessels, but can also be present in organs such as the brain, lungs, spleen and liver. As with other lymphoproliferative disorders, ACIS carries an increased risk of developing non-Hodgkin's lymphoma. Treatment for ACIS varies depending on its location, but usually involves a combination of topical medications, radiation therapy or surgery to remove any affected areas.
ACIS meaning in Syndromes in Medical
ACIS mostly used in an acronym Syndromes in Category Medical that means Acquired Cellular Induration Syndrome
Shorthand: ACIS,
Full Form: Acquired Cellular Induration Syndrome
For more information of "Acquired Cellular Induration Syndrome", see the section below.
Definition
Acquired Cellular Induration Syndrome (ACIS) is a rare form of lymphoproliferative disorder characterized by an abnormal growth of normal cells and tissues that results in thickening or induration at the site. This condition typically affects the skin as well as other organs such as the brain, lungs, spleen and liver. While typically benign in nature, there is an increased risk of developing non-Hodgkin’s lymphoma associated with this condition.
Symptoms
The symptoms of ACIS vary depending on where it is located within the body; however common signs include painless thickening or hardening in one specific area along with redness around it; enlargement; itching or tingling sensations; tenderness at touch; swelling; warmth to touch; and/or discoloration around the thickened region. Additionally, some individuals may also experience fatigue if their affected organ(s) are involved.
Diagnosis & Treatment
In order to diagnose ACIS, physicians will conduct a physical exam along with laboratory tests such as biopsies or imaging studies. Treatment depends largely on where ACIS is located--topical medications might be utilized if it affects only one small area whereas surgery will be required if there are multiple affected areas requiring removal or if any organs are involved. In some cases radiation therapy may also be necessary for those who do not respond well to other forms treatments.
Essential Questions and Answers on Acquired Cellular Induration Syndrome in "MEDICAL»SYNDROMES"
What is ACIS?
Acquired Cellular Induration Syndrome (ACIS) is a rare autoimmune disorder that results in thickening and hardening of the skin, typically affecting the extremities. It is also known as dermatoporosis. It is an acquired condition, meaning it develops with age rather than being present at birth.
Who can get ACIS?
Although the exact cause of ACIS remains unknown, it appears to be more common among older adults. Women may be more likely to develop this disorder than men, and there are no racial predispositions for ACIS.
How is ACIS diagnosed?
To diagnose ACIS, your doctor will perform a physical exam and might order X-rays or other imaging tests. Your doctor may also take a sample of your skin for examination under a microscope. This process is called biopsy.
What are the symptoms of ACIS?
The main symptom of ACIS is thickened, hardened areas of skin on the arms and legs that appear without warning. Other symptoms can include pain and itching in the affected areas. In some cases, ulcers may form if areas become very thickened or lifeless due to lack of blood supply.
What complications can result from ACIS?
Complications related to ACIS primarily involve difficulty with mobility due to joint contractures caused by tightened skin and impaired circulation due to decreased movement within affected areas of skin.
How is ACIS treated?
Treatment for ACIS typically involves medications such as immunosuppressants or corticosteroids to reduce inflammation and regulate immune system activity. Physical therapy can help maintain mobility by stretching tight skin and muscles around affected joints.
Is surgery required for treatment of ACIS?
Surgery may be indicated if nonsurgical treatments are ineffective or not feasible in certain patients with severe cases of ACIS, where large amounts of tissue have been hardened or necrotic (dead) parts require removal.
Can lifestyle changes help manage symptoms associated with ACIS?
Lifestyle modifications that focus on maintaining good range-of-motion exercises are useful in managing symptoms associated with this condition such as reduced levels of extracellular matrix proteins which provide support to surrounding tissues.
Final Words:
Acquired Cellular Induration Syndrome (ACIS) is a rare form of lymphoproliferative disorder characterized by an abnormal growth of normal cells and tissues resulting in induration or thickening at the site affected. Common symptoms include painless thickening or hardening along with redness around it and other signs such as enlargement, itching/tingling sensations and discoloration at times when organs are involved too. Diagnosis requires physical exam along with laboratory tests while treatment usually consists of topical medications combined with radiation therapy and/or surgery to remove any affected areas depending upon its location coupled with severity level.
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