What does CCPA mean in UNCLASSIFIED
Catabolite control protein A (CCPA) is an abbreviation commonly used in the field of molecular biology. It refers to a transcription factor that belongs to the family of cAMP-dependent transcription regulators, and plays a key role in controlling cellular metabolism and gene expression. CCPA has been extensively studied by researchers, who have determined its structure, regulation, and functions. In this article, we'll take a closer look at CCPA and explore what it means and how it plays an important role in molecular biology.
CCPA meaning in Unclassified in Miscellaneous
CCPA mostly used in an acronym Unclassified in Category Miscellaneous that means Catabolite control protein A
Shorthand: CCPA,
Full Form: Catabolite control protein A
For more information of "Catabolite control protein A", see the section below.
What is Catabolite Control Protein A (CCPA)?
Catabolite Control Protein A (CCPA) is a transcription factor found in all eukaryotic cells. It belongs to the cAMP-dependent transcription regulator family, which are involved in regulating gene expression. This protein plays an important role in catabolic processes and metabolic homeostasis in response to cellular stresses such as nutrient availability or osmolality stress.[1] The current understanding suggests that CCPA regulates both catabolic and anabolic pathways by increasing the activities of enzymes involved in the breakdown of carbohydrates or proteins while simultaneously repressing those responsible for synthesis.[2] Additionally, it has been shown to regulate mRNA stability and translation initiation.[3]
Structure & Regulation
The CCPA protein contains several protein domains that have been well studied and described; these include an N-terminal transactivation domain (TAD), two DNA binding domains (DBD), two spectrin repeats, an OCS domain, two Zn fingers, as well as a C-terminal dimerization domain.[4][5] The main regulatory mechanism of CCPA involves changes in intracellular concentrations of cAMP or cGMP, which can be modulated by hormones or other environmental signals such as nutrient deprivation. These molecules bind to specific sites on the CCPA protein causing structural changes that ultimately influence its activity.[6][7]
Functions
The main function of CCPA is to act as a key regulator of metabolism during times when there is limited nutrition availablility or physiological stress. It does this by modulating various enzymatic activities that either break down macromolecules for energy production or synthesize new macromolecules for storage purposes.[8][9] For instance, during periods of starvation when glucose levels are low, CCPA activates glycolysis enzymes while repressing gluconeogenesis enzyme activities so that more energy can be produced from existing sources.[10] Another important function includes regulating mRNA stability and translation initiation where certain mRNAs will be stabilized while others will be degraded depending on the need for gene expression under varying conditions[11].
Essential Questions and Answers on Catabolite control protein A in "MISCELLANEOUS»UNFILED"
In conclusion, Catabolite Control Protein A (CCPA) is an important regulatory element that plays a significant role in controlling metabolic processes across all living organisms. Its structure consists of several distinct domains with each playing their own unique part in regulation via hormone signaling or environmental cues such as nutrition levels. Furthermore, its functions are varied with it being involved in both catabolic processes such as glycolysis while also having a hand in controlling mRNA stability for efficient gene expression.
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