What does CDKA mean in BIOLOGY

A cyclin-dependent kinase (CDK) is a type of protein that is involved in regulating the progression of the cell cycle by controlling key biochemical events. CDKs typically act together with other proteins called cyclins, which are responsible for activating or deactivating them at different stages in the cell cycle.

Cyclin dependent kinases are activated when they form complexes with specific cyclins and other regulatory proteins and become active when these complexes affect substrates via phosphorylation. The action of these enzymes helps to regulate critical steps during the transition from one phase to another in the cell cycle.

The main role of CDKs is to control key biochemical events that regulate the progression of the cell cycle by assisting with cellular processes like DNA replication, chromosome condensation, spindle formation and mitosis. They also control metabolic pathways related to growth and differentiation and help regulate gene expression, protein synthesis, RNA processing and chromatin remodeling.

If there is an abnormality or dysregulation in CDK activity then it can lead to uncontrolled proliferation or apoptosis causing developmental defects or cancer. In addition, mutations in certain genes encoding for proteins involved in CDK-mediated pathways can cause human diseases such as Brugada Syndrome, Bjornstad Syndrome and Progeria Syndrome among others.