What does SFDT mean in UNCLASSIFIED
SFDT stands for Sabin Feldman Dye Test. It is a laboratory test used to assess the immune response to the poliovirus. The test is named after its developers, Albert Sabin and Herman Feldman.
SFDT meaning in Unclassified in Miscellaneous
SFDT mostly used in an acronym Unclassified in Category Miscellaneous that means Sabin Feldman Dye Test
Shorthand: SFDT,
Full Form: Sabin Feldman Dye Test
For more information of "Sabin Feldman Dye Test", see the section below.
Principle
The SFDT is based on the principle that antibodies produced by the immune system can neutralize viruses. In this test, a sample of the patient's serum is mixed with a known amount of poliovirus. If the patient has antibodies against the poliovirus, they will bind to the virus and prevent it from infecting susceptible cells.
Procedure
The SFDT is performed using the following steps:
- A blood sample is collected from the patient.
- The serum is separated from the blood cells.
- The serum is mixed with a known concentration of poliovirus.
- The mixture is incubated for a period of time.
- The mixture is then added to a cell culture.
- The cell culture is observed for the presence of viral replication.
Interpretation
If the cell culture shows no evidence of viral replication, it means that the patient has antibodies against the poliovirus and is immune to the infection. If the cell culture shows evidence of viral replication, it means that the patient does not have antibodies against the poliovirus and is not immune to the infection.
Applications
The SFDT is used for the following purposes:
- To determine the immune status of individuals for poliovirus.
- To evaluate the efficacy of polio vaccines.
- To monitor the spread of poliovirus in a population.
Essential Questions and Answers on Sabin Feldman Dye Test in "MISCELLANEOUS»UNFILED"
What is the Sabin Feldman Dye Test (SFDT)?
The Sabin Feldman Dye Test (SFDT) is a laboratory test used to diagnose dengue fever and differentiate it from other similar infections. It detects antibodies produced by the body's immune system in response to the dengue virus.
How is the SFDT performed?
A blood sample is taken from the patient and tested for the presence of dengue-specific antibodies. The test involves adding a dye to the blood sample and observing the reaction.
When is the SFDT most useful?
The SFDT is most useful in the early stages of dengue fever, when other tests may not be conclusive. It can also be used to differentiate dengue fever from other infections, such as chikungunya and yellow fever.
What are the limitations of the SFDT?
The SFDT can sometimes give false-negative results, especially in the early stages of dengue fever. It is also not able to distinguish between different serotypes of the dengue virus.
How accurate is the SFDT?
The SFDT is generally considered to be a reliable test for diagnosing dengue fever. However, it is important to remember that no test is 100% accurate.
Final Words: The SFDT is a valuable tool for assessing the immune response to the poliovirus. It is used to diagnose polio infections and to evaluate the effectiveness of polio vaccines. The test is also used to monitor the spread of poliovirus in a population.