What does GS-5734 mean in VACCINE
GS-5734 is a codename for an antiviral medication known as Remdesivir. It is developed by Gilead Sciences, a biopharmaceutical company based in California, United States. Remdesivir is used to treat viral infections, particularly those caused by RNA viruses, such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes COVID-19.
GS-5734 meaning in Vaccine in Medical
GS-5734 mostly used in an acronym Vaccine in Category Medical that means Remdesivir
Shorthand: GS-5734,
Full Form: Remdesivir
For more information of "Remdesivir", see the section below.
Mechanism of Action
Remdesivir is a nucleotide analog that mimics adenosine, a key component of RNA. When incorporated into viral RNA during replication, it causes chain termination, effectively inhibiting viral replication and reducing viral load.
Clinical Applications
Remdesivir has been approved for use in the treatment of COVID-19 in adults and children aged 12 years and older who require hospitalization. It is administered intravenously over a period of 3 to 5 days.
Efficacy and Safety
Clinical trials have shown that Remdesivir can reduce the time to recovery from COVID-19 and improve clinical outcomes in hospitalized patients. It has also been found to be generally safe and well-tolerated, with the most common side effects including nausea, vomiting, and headache.
Essential Questions and Answers on Remdesivir in "MEDICAL»VACCINE"
What is GS-5734?
GS-5734 is an investigational antiviral drug developed by Gilead Sciences. It is also known by its generic name, remdesivir.
How does GS-5734 work?
GS-5734 is a nucleotide analogue that targets the RNA polymerase of SARS-CoV-2, the virus that causes COVID-19. It interferes with the virus's ability to replicate, thereby slowing or halting its spread.
Who can use GS-5734?
GS-5734 is currently authorized for emergency use in the United States for the treatment of hospitalized COVID-19 patients aged 12 and older who require oxygen support.
How is GS-5734 administered?
GS-5734 is administered intravenously over a period of 3 to 5 days. The usual dose is 200 mg on the first day, followed by 100 mg daily for the remaining days of treatment.
What are the side effects of GS-5734?
The most common side effects of GS-5734 include nausea, vomiting, diarrhea, headache, and increased liver enzymes.
How effective is GS-5734?
Clinical trials have shown that GS-5734 can reduce the time to recovery in hospitalized COVID-19 patients by an average of 4 days. It has also been shown to reduce the risk of death in these patients.
Is GS-5734 safe for use in pregnant women and children?
The safety and efficacy of GS-5734 in pregnant women and children have not been fully established. It should only be used in these populations if the potential benefits outweigh the risks.
What is the future of GS-5734?
Gilead Sciences is continuing to study GS-5734 in clinical trials to assess its potential for treating other viral infections, including those caused by coronaviruses and filoviruses.
Final Words: GS-5734 (Remdesivir) is an effective antiviral medication used to treat COVID-19 and other RNA virus infections. It has demonstrated promising results in reducing viral load, improving patient outcomes, and shortening hospital stays.