What does PRS mean in UNCLASSIFIED


PRS (Pierre Robin Sequence) is a rare congenital birth defect that affects the development of the jaw and airway. It is characterized by three main features: micrognathia (small lower jaw), glossoptosis (posterior displacement of the tongue), and airway obstruction.

PRS

PRS meaning in Unclassified in Miscellaneous

PRS mostly used in an acronym Unclassified in Category Miscellaneous that means Pierre Robin Sequence

Shorthand: PRS,
Full Form: Pierre Robin Sequence

For more information of "Pierre Robin Sequence", see the section below.

» Miscellaneous » Unclassified

PRS Meaning

PRS stands for Pierre Robin Sequence, named after the French pediatrician who first described it in 1923. It is a genetic condition that occurs in approximately 1 in 8,500 live births.

Clinical Features

The classic triad of PRS includes:

  • Micrognathia: The lower jaw (mandible) is small and underdeveloped.
  • Glossoptosis: The tongue falls back into the airway, obstructing the passage of air.
  • Airway Obstruction: The small jaw and recessed tongue can cause breathing difficulties, especially during feeding and sleep.

Complications

Untreated PRS can lead to several complications, including:

  • Respiratory distress
  • Feeding difficulties
  • Growth retardation
  • Dental problems
  • Speech impairment

Treatment

Treatment for PRS typically involves a multidisciplinary approach, including:

  • Airway Management: Airway support may be provided through intubation, tracheostomy, or CPAP therapy.
  • Jaw Advancement Surgery: Surgery to reposition the lower jaw and correct micrognathia.
  • Tongue-Lip Adhesion (TLA): A surgical procedure that secures the tongue to the lower lip, preventing it from falling back into the airway.
  • Palatal Expansion: Expansion of the palate to create more space for the tongue.

Essential Questions and Answers on Pierre Robin Sequence in "MISCELLANEOUS»UNFILED"

What is Pierre Robin Sequence (PRS)?

PRS is a rare genetic disorder characterized by a triad of features: micrognathia (small jaw), glossoptosis (tongue falling back into the throat), and airway obstruction.

What are the symptoms of PRS?

Symptoms may vary in severity and can include difficulty breathing, feeding problems, facial abnormalities, speech impairments, and developmental delays.

What causes PRS?

The exact cause of PRS is unknown, but it is believed to involve a combination of genetic and environmental factors.

How is PRS diagnosed?

PRS is typically diagnosed based on the characteristic triad of features, as well as a physical examination and imaging studies, such as an X-ray or CT scan.

How is PRS treated?

Treatment for PRS depends on the severity of the disorder. It may involve surgery to correct the airway obstruction, assistive breathing devices, speech therapy, and nutritional support.

What is the prognosis for PRS?

The prognosis for PRS varies depending on the severity of the disorder. With early diagnosis and treatment, most individuals can live full and active lives.

What are the potential complications of PRS?

Complications of PRS can include growth and developmental delays, hearing loss, and heart defects.

Is there a cure for PRS?

There is currently no cure for PRS, but treatment can significantly improve the quality of life for affected individuals.

Final Words: PRS is a complex birth defect that requires prompt medical attention and specialized care. By understanding the condition and seeking early intervention, the long-term outcomes for individuals with PRS can be significantly improved.

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