What does HTR mean in UNCLASSIFIED
Hemolytic Transfusion Reaction (HTR) is a serious and potentially life-threatening condition that occurs when the recipient's immune system attacks the transfused blood cells. This reaction is caused by incompatibility between the donor's and recipient's blood types, leading to the destruction of red blood cells.
HTR meaning in Unclassified in Miscellaneous
HTR mostly used in an acronym Unclassified in Category Miscellaneous that means Hemolytic Transfusion Reaction
Shorthand: HTR,
Full Form: Hemolytic Transfusion Reaction
For more information of "Hemolytic Transfusion Reaction", see the section below.
Causes of HTR
- ABO incompatibility: The most common cause of HTR is when the recipient's blood type contains antibodies that attack the antigens on the donor's red blood cells.
- Rh incompatibility: This occurs when the recipient is Rh-negative (lacks the Rh antigen) and receives blood from an Rh-positive donor.
Symptoms of HTR
Symptoms of HTR can develop within minutes or hours after the transfusion and may include:
- Fever
- Chills
- Hemoglobinuria (urine that is red due to the presence of hemoglobin)
- Hypotension (low blood pressure)
- Confusion
- Seizures
- Kidney failure
Treatment of HTR
Prompt treatment of HTR is crucial to prevent severe complications and death. Treatment may include:
- Stopping the transfusion immediately
- Administering fluids and medications to maintain blood pressure
- Providing oxygen therapy
- Exchanging the patient's blood (exchange transfusion)
Prevention of HTR
To prevent HTR, it is essential to perform meticulous blood type testing before transfusions to ensure compatibility. This includes:
- Blood typing: Determining the recipient's and donor's blood types.
- Crossmatching: Mixing the recipient's serum with the donor's red blood cells to detect any incompatibilities.
Essential Questions and Answers on Hemolytic Transfusion Reaction in "MISCELLANEOUS»UNFILED"
What is a Hemolytic Transfusion Reaction (HTR)?
HTR occurs when transfused red blood cells are destroyed by the recipient's immune system. This can lead to serious complications and even death.
What are the symptoms of HTR?
Symptoms of HTR can range from mild to severe and include: fever, chills, low blood pressure, nausea, vomiting, hemoglobinuria (red urine), shock, and kidney failure.
What causes HTR?
HTR is most commonly caused by ABO and Rh blood group incompatibility, where the recipient's antibodies attack the transfused red blood cells. Other causes include:
- Platelet transfusion refractoriness
- Red cell antigen-antibody mismatch
- Bacterial contamination of blood products
How is HTR diagnosed?
HTR is diagnosed based on the patient's symptoms, laboratory tests, and a review of the patient's transfusion history.
How is HTR treated?
Treatment for HTR depends on the severity of the reaction and may include:
- Stopping the transfusion
- Administering fluids and medications to support blood pressure
- Dialysis to remove hemoglobin from the blood
- Blood transfusions to replace destroyed red blood cells
How can HTR be prevented?
HTR can be prevented by:
- Careful blood typing and crossmatching before transfusion
- Using leukocyte-reduced blood products
- Monitoring patients closely during and after transfusions
Final Words: HTR is a potentially life-threatening condition that can occur due to blood type incompatibility during transfusions. Prompt recognition and treatment are crucial to minimize complications. By adhering to strict blood typing and crossmatching procedures, HTR can be largely prevented, ensuring the safety of transfusion practices.
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