What does MDBK mean in MEDICAL
MDBK stands for Madin Darby Bovine Kidney. It refers to a cell line derived from the kidney tissue of a bovine fetus. This cell line has been widely used in virology research and vaccine production due to its ability to support the replication of a broad range of viruses.
MDBK meaning in Medical in Medical
MDBK mostly used in an acronym Medical in Category Medical that means Madin Darby Bovine Kidney
Shorthand: MDBK,
Full Form: Madin Darby Bovine Kidney
For more information of "Madin Darby Bovine Kidney", see the section below.
Properties of MDBK Cells
- Epithelial morphology: MDBK cells exhibit a polygonal shape and a cobblestone-like appearance when grown in culture.
- Adherent growth: They adhere tightly to the culture surface and form a monolayer.
- Susceptibility to viruses: MDBK cells are highly susceptible to a wide variety of viruses, including those that cause respiratory infections, gastroenteritis, and herpes.
- Rapid proliferation: MDBK cells grow rapidly in culture, making them suitable for large-scale production of viruses.
Applications of MDBK Cells
- Virology research: MDBK cells are commonly used in virology research to study virus-cell interactions, viral replication, and vaccine development.
- Vaccine production: MDBK cells are used as a substrate for the production of various vaccines, such as the rabies vaccine, polio vaccine, and measles vaccine.
- Diagnostic virology: MDBK cells are employed in diagnostic virology to isolate and identify viruses from clinical samples.
- Cell biology: MDBK cells have also been used in cell biology studies to investigate cell membrane dynamics, cell signaling pathways, and viral entry mechanisms.
Essential Questions and Answers on Madin Darby Bovine Kidney in "MEDICAL»MEDICAL"
What is MDBK?
MDBK stands for Madin Darby Bovine Kidney, a type of cell line derived from the kidney of a bovine (cow). This cell line is commonly used in laboratory research and production of vaccines and biological products.
What are the characteristics of MDBK cells?
MDBK cells are adherent, meaning they attach to a surface and grow as a monolayer. They are highly susceptible to a wide range of viruses, including bovine viruses, influenza viruses, and adenoviruses. MDBK cells are relatively easy to culture and maintain in the laboratory.
What are the applications of MDBK cells?
MDBK cells are widely used in virology research for the isolation, cultivation, and propagation of viruses. They are also used in vaccine production, as they can support the growth of many vaccine-producing viruses. Additionally, MDBK cells are used in toxicology studies and as a model for studying bovine kidney function and disease.
Final Words: MDBK cells are a valuable tool in virology research and vaccine production. Their susceptibility to viruses, rapid proliferation, and ease of culture make them an ideal substrate for studying viruses and developing effective vaccines.