What does PGT mean in HUMAN GENOME

Preimplantation Genetic Testing (PGT) is a group of techniques used to screen embryos for genetic conditions before they are implanted into the uterus. PGT can identify a variety of genetic abnormalities, including chromosomal abnormalities and specific gene mutations.

There are several different types of PGT, including:

• PGT-A: Tests for chromosomal abnormalities, such as Down syndrome and Trisomy 18.
• PGT-M: Tests for specific gene mutations known to cause genetic disorders.
• PGT-SR: Tests for specific genetic rearrangements that may increase the risk of certain diseases.

PGT is recommended for couples with a known risk of passing on a genetic condition to their child, such as those with a family history of genetic disorders, advanced maternal age, or previous pregnancies with genetic abnormalities.

PGT is performed during the in vitro fertilization (IVF) process. After eggs are fertilized in the lab, a few cells are removed from each embryo for testing. The genetic material in these cells is then analyzed to identify any abnormalities.

PGT is highly accurate, but no test is 100% reliable. The accuracy of PGT depends on the type of test being performed and the specific genetic condition being tested for.

PGT is a relatively safe procedure, but there are some potential risks, including the risk of embryo damage and the risk of false positive or false negative results.

The cost of PGT varies depending on the type of test being performed and the clinic or lab performing the test. In general, PGT-A is the most affordable type of PGT, while PGT-M is the most expensive.

PGT raises a number of ethical concerns, such as the potential for discrimination against embryos with genetic conditions and the potential to create "designer babies." It is important to carefully consider the ethical implications of PGT before making a decision about whether or not to undergo the procedure.