What does ERPC mean in UNCLASSIFIED
ERPC stands for E Rosette Positive Colonies. It is a laboratory test used to measure the number of T lymphocytes (a type of white blood cell) that have receptors for sheep red blood cells (SRBCs).
ERPC meaning in Unclassified in Miscellaneous
ERPC mostly used in an acronym Unclassified in Category Miscellaneous that means E Rosette Positive Colonies
Shorthand: ERPC,
Full Form: E Rosette Positive Colonies
For more information of "E Rosette Positive Colonies", see the section below.
Understanding ERPC
ERPC is a measure of T cell function and is used to assess the immune system's ability to recognize and respond to foreign invaders, such as viruses and bacteria. The test involves incubating the patient's blood sample with SRBCs. T lymphocytes that have receptors for SRBCs will bind to them, forming E rosettes. The number of E rosettes formed is then counted under a microscope.
Normal ERPC Values
Normal ERPC values vary depending on the laboratory and the method used. Generally, values between 5% and 15% are considered normal.
Clinical Significance
Low ERPC values may indicate T cell dysfunction, which can be caused by:
- Immunodeficiency disorders
- Autoimmune diseases
- HIV infection
- Malnutrition
- Certain medications
High ERPC values are less common and may be associated with:
- Certain infections, such as Epstein-Barr virus
- Autoimmune diseases, such as rheumatoid arthritis
Essential Questions and Answers on E Rosette Positive Colonies in "MISCELLANEOUS»UNFILED"
What are E Rosette Positive Colonies (ERPC)?
E Rosette Positive Colonies (ERPC) are a measure of T cell function. T cells are a type of white blood cell that plays a role in the immune response. ERPC are formed when T cells bind to sheep red blood cells (SRBCs) that have been coated with antibodies. The number of ERPC can be used to assess the function of T cells.
What is the significance of ERPC in HIV infection?
In HIV infection, ERPC can be used to assess the severity of the disease. Low ERPC counts are associated with more severe disease and a higher risk of opportunistic infections. ERPC counts can also be used to monitor the response to antiretroviral therapy (ART).
How is the ERPC test performed?
The ERPC test is performed by mixing a sample of the patient's blood with SRBCs that have been coated with antibodies. The mixture is then incubated and the number of ERPC is counted.
What are normal ERPC levels?
Normal ERPC levels vary depending on the laboratory performing the test. However, a typical normal range is 15-35%.
What factors can affect ERPC levels?
ERPC levels can be affected by a number of factors, including:
- HIV infection
- Other infections
- Immunosuppressive drugs
- Age
- Gender
Final Words: ERPC is a valuable laboratory test for evaluating the immune system's ability to recognize and respond to foreign invaders. Abnormal ERPC values can provide insights into underlying health conditions and guide appropriate medical management.
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