What does CPA mean in UNCLASSIFIED

CPA Meaning

CPA stands for Chronic Pulmonary Aspergillosis. It is a long-term fungal infection that affects the lungs. The term "chronic" refers to its persistent and often debilitating nature.

Causes of CPA

CPA is primarily caused by the Aspergillus fungus, commonly found in soil, air, and decaying vegetation. Individuals with impaired immune systems, such as those with organ transplants, HIV/AIDS, or certain genetic disorders, are at increased risk of developing CPA. Other risk factors include:

• Prolonged use of corticosteroids or other immunosuppressive medications
• Chronic lung diseases like cystic fibrosis, chronic obstructive pulmonary disease (COPD), or asthma
• History of lung damage or surgery

Symptoms of CPA

Symptoms of CPA vary depending on the severity of the infection. Common signs include:

• Persistent cough with or without sputum production
• Shortness of breath and wheezing
• Chest pain
• Fever and chills
• Fatigue and weakness
• Weight loss

Diagnosis of CPA

Diagnosing CPA can be challenging due to its nonspecific symptoms. Typically, doctors consider a combination of factors, including:

• Medical history and physical examination
• Chest X-ray or CT scan
• Sputum culture or biopsy
• Blood tests for fungal antibodies

Treatment of CPA

Treatment for CPA aims to control the infection and prevent further lung damage. It usually involves:

• Antifungal Medications: Long-term administration of antifungal drugs like itraconazole or voriconazole
• Surgery: In severe cases, surgical removal of affected lung tissue may be necessary
• Other Medications: Bronchodilators to relieve airway obstruction and corticosteroids to reduce inflammation