What does ADHH mean in UNCLASSIFIED
ADHH stands for Autosomal Dominant Hypocalcaemia Hypercalciuria. It is a rare genetic disorder characterized by low levels of calcium (hypocalcaemia) and high levels of calcium in the urine (hypercalciuria). ADHH is a lifelong condition that can be managed with treatment.
ADHH meaning in Unclassified in Miscellaneous
ADHH mostly used in an acronym Unclassified in Category Miscellaneous that means Autosomal Dominant Hypocalcaemia Hypercalciuria
Shorthand: ADHH,
Full Form: Autosomal Dominant Hypocalcaemia Hypercalciuria
For more information of "Autosomal Dominant Hypocalcaemia Hypercalciuria", see the section below.
Symptoms
The most common symptoms of ADHH include:
- Muscle weakness and cramps
- Fatigue
- Bone pain
- Kidney stones
- Increased thirst
- Frequent urination
Causes
ADHH is caused by mutations in the CASR gene. This gene encodes the calcium-sensing receptor, which is responsible for regulating calcium levels in the body. Mutations in the CASR gene can lead to decreased sensitivity to calcium, which can cause the body to lose too much calcium in the urine.
Diagnosis
ADHH is diagnosed based on the patient's symptoms, a physical examination, and blood and urine tests. Blood tests can measure calcium levels, while urine tests can measure calcium levels and levels of other minerals, such as phosphate and magnesium.
Treatment
There is no cure for ADHH, but treatment can help to manage the condition and prevent complications. Treatment typically includes:
- Calcium supplements
- Vitamin D supplements
- Medications to reduce calcium loss in the urine
- Lifestyle changes, such as drinking plenty of fluids and eating a healthy diet
Essential Questions and Answers on Autosomal Dominant Hypocalcaemia Hypercalciuria in "MISCELLANEOUS»UNFILED"
What is ADHH (Autosomal Dominant Hypocalcaemia Hypercalciuria)?
ADHH is a rare genetic disorder that affects the body's ability to regulate calcium levels. It is characterized by low blood calcium levels (hypocalcaemia) and high levels of calcium in the urine (hypercalciuria).
What causes ADHH?
ADHH is caused by mutations in the CASR gene, which encodes the calcium-sensing receptor. This receptor normally detects changes in blood calcium levels and helps to regulate the body's response. Mutations in the CASR gene can lead to a defective receptor that does not function properly, resulting in ADHH.
What are the symptoms of ADHH?
Symptoms of ADHH can vary, but may include:
- Muscle weakness, cramps, or spasms
- Numbness or tingling in the hands or feet
- Seizures
- Cataracts
- Kidney stones
- Osteoporosis
- Fatigue
- Anxiety
- Depression
How is ADHH diagnosed?
ADHH is typically diagnosed based on blood tests that show low calcium levels and high calcium levels in the urine. Genetic testing can also be used to confirm the diagnosis.
How is ADHH treated?
Treatment for ADHH focuses on managing the symptoms and preventing complications. This may include:
- Calcium supplements
- Vitamin D supplements
- Medications to reduce calcium loss in the urine
- Surgery to remove cataracts or kidney stones
- Lifestyle changes, such as avoiding caffeine and alcohol
What is the prognosis for ADHH?
The prognosis for ADHH varies depending on the severity of the symptoms. With proper treatment, most individuals with ADHH can live normal, healthy lives. However, it is important to monitor calcium levels regularly and to seek medical attention if symptoms worsen.
Final Words: ADHH is a rare genetic disorder that can lead to low calcium levels and high calcium levels in the urine. The condition can be managed with treatment, which typically includes calcium and vitamin D supplements, medications, and lifestyle changes.