What does AMPE mean in UNCLASSIFIED

Acute massive pulmonary embolism (AMPE) is a sudden and severe blockage of one or more pulmonary arteries in the lungs caused by a blood clot. It can cause decreased oxygen levels in the body, reduced blood flow to the heart, and low blood pressure.

Those at risk for AMPE include those who have recently undergone major surgery or trauma, those with venous thromboembolism or deep vein thrombosis, and those with inherited clotting disorders. Additionally, pregnant women are at increased risk for developing AMPE.

Symptoms of AMPE vary depending on how much of the lung is blocked but can include shortness of breath, chest pain that worsens with deep breaths, coughing up blood and fainting. In some cases, there may be no symptoms until the blockage has become life-threatening.

Diagnosis usually involves imaging tests such as CT scans or echocardiograms to visualize the location of the clot within the pulmonary artery. Typically other tests such as arterial blood gas analysis and pulse oximetry are also done to assess oxygen levels and pulmonary function.

Treatment options may include using medications such as anticoagulants or thrombolytics to dissolve clots as well as surgical interventions like removing part of a clot or stenting an artery to increase blood flow in certain cases. Therapy should be individualized depending on severity and timing of diagnosis.