What does AHTR mean in UNCLASSIFIED
Acute Hypotensive Transfusion Reaction (AHTR) is a rare but serious complication that can occur during or shortly after a blood transfusion. It is characterized by a sudden and severe drop in blood pressure, which can lead to shock and even death.
AHTR meaning in Unclassified in Miscellaneous
AHTR mostly used in an acronym Unclassified in Category Miscellaneous that means Acute Hypotensive Transfusion Reaction
Shorthand: AHTR,
Full Form: Acute Hypotensive Transfusion Reaction
For more information of "Acute Hypotensive Transfusion Reaction", see the section below.
Definition
AHTR is defined as a transfusion reaction that causes a decrease in systolic blood pressure of at least 30 mmHg or a drop in mean arterial pressure of at least 20 mmHg within 30 minutes of the start of a transfusion.
Symptoms
The symptoms of AHTR can appear suddenly and include:
- Hypotension (low blood pressure)
- Dizziness or lightheadedness
- Confusion
- Nausea or vomiting
- Chest pain or shortness of breath
- Cardiac arrhythmias
Causes
The exact cause of AHTR is unknown, but it is thought to be related to an immune reaction to transfused blood products. This reaction can cause the release of inflammatory mediators, which can lead to vasodilation (widening of blood vessels) and a drop in blood pressure.
Risk Factors
The risk factors for AHTR include:
- Previous history of AHTR
- Transfusion of large volumes of blood or blood products
- Transfusion of blood products from an incompatible donor
- Underlying medical conditions that can affect the immune system, such as autoimmune disorders or cancer
Treatment
The treatment for AHTR is supportive and includes:
- Stopping the transfusion
- Administering fluids and vasopressors to raise blood pressure
- Monitoring the patient's vital signs and providing oxygen support as needed
Prevention
There is no way to completely prevent AHTR, but the following measures can help to reduce the risk:
- Careful screening of blood donors
- Proper matching of blood products to recipients
- Slow infusion of blood products
- Monitoring the patient's vital signs during and after a transfusion
Conclusion
AHTR is a rare but potentially fatal complication of blood transfusions. By understanding the symptoms, causes, and risk factors of AHTR, healthcare professionals can take steps to reduce the risk of this reaction and provide prompt treatment if it does occur.
Essential Questions and Answers on Acute Hypotensive Transfusion Reaction in "MISCELLANEOUS»UNFILED"
What is an AHTR?
AHTR (Acute Hypotensive Transfusion Reaction) is a rare but serious complication that can occur during a blood transfusion. It is characterized by a sudden and severe drop in blood pressure, which can lead to shock and even death.
What causes an AHTR?
AHTRs are caused by the presence of antibodies in the recipient's blood that react with antigens on the donor's red blood cells. This reaction can cause the recipient's red blood cells to rupture, releasing harmful substances into the bloodstream.
What are the symptoms of an AHTR?
The symptoms of an AHTR can include:
- Sudden drop in blood pressure
- Shock
- Shortness of breath
- Chest pain
- Confusion
- Nausea and vomiting
How is an AHTR treated?
The treatment for an AHTR involves stopping the transfusion and administering fluids and medications to stabilize the patient's blood pressure. In severe cases, the patient may need to be intubated and placed on a ventilator.
How can AHTRs be prevented?
AHTRs can be prevented by carefully matching the donor's blood type with the recipient's blood type. In some cases, patients may need to be tested for antibodies before receiving a transfusion.