What does APRBC mean in CANCER
APRBC stands for Anthracycline Primary Resistant Breast Cancer. It is a type of breast cancer that does not respond to treatment with anthracyclines, which are a class of chemotherapy drugs commonly used to treat breast cancer.
APRBC meaning in Cancer in Medical
APRBC mostly used in an acronym Cancer in Category Medical that means Anthracycline Primary Resistant Breast Cancer
Shorthand: APRBC,
Full Form: Anthracycline Primary Resistant Breast Cancer
For more information of "Anthracycline Primary Resistant Breast Cancer", see the section below.
Causes of APRBC
The exact cause of APRBC is unknown, but it is believed to be due to genetic mutations that make the cancer cells resistant to anthracyclines. These mutations can occur in genes that are involved in DNA repair, drug transport, or the cell cycle.
Symptoms of APRBC
APRBC typically presents with symptoms similar to other types of breast cancer, such as:
- A lump or thickening in the breast
- Changes in the shape or size of the breast
- Nipple discharge
- Pain or tenderness in the breast
Diagnosis of APRBC
APRBC is diagnosed based on a biopsy of the breast tumor. The biopsy sample is tested to determine if the cancer cells are resistant to anthracyclines.
Treatment of APRBC
APRBC is more difficult to treat than other types of breast cancer due to its resistance to anthracyclines. Treatment options may include:
- Surgery to remove the tumor
- Radiation therapy
- Chemotherapy with drugs other than anthracyclines
- Targeted therapy
- Immunotherapy
Essential Questions and Answers on Anthracycline Primary Resistant Breast Cancer in "MEDICAL»CANCER"
What is Anthracycline Primary Resistant Breast Cancer (APRBC)?
APRBC is a type of breast cancer that does not respond to anthracyclines, which are a class of chemotherapy drugs commonly used to treat breast cancer. Anthracyclines work by damaging the DNA of cancer cells, preventing them from dividing and multiplying. However, in APRBC, the cancer cells have developed resistance to this mechanism, making the drugs ineffective.
What are the symptoms of APRBC?
APRBC typically presents with the same symptoms as other types of breast cancer, such as a lump or thickening in the breast, changes in the skin texture or nipple, and breast pain. However, the lack of response to anthracycline therapy may be a clue to the diagnosis.
How is APRBC diagnosed?
APRBC is diagnosed through a combination of physical examination, imaging tests such as mammograms and biopsies. The biopsy sample is then analyzed to determine the cancer's characteristics, including its resistance to anthracyclines.
What are the treatment options for APRBC?
Treatment options for APRBC are limited due to the resistance to anthracyclines. However, alternative therapies may include other chemotherapy drugs, targeted therapies that inhibit specific molecules involved in cancer growth, and hormone therapy. Surgery, radiation therapy, and immunotherapy may also be considered.
What is the prognosis for APRBC?
The prognosis for APRBC depends on factors such as the stage of the cancer, the overall health of the patient, and the response to treatment. While APRBC can be a challenging diagnosis, advancements in targeted therapies and personalized medicine offer hope for improved outcomes.
Final Words: APRBC is a challenging type of breast cancer to treat. However, there are a variety of treatment options available, and research is ongoing to develop new and more effective therapies.