What does CHARGE mean in ONCOLOGY
CHARGE is a rare genetic disorder characterized by a specific combination of anomalies affecting multiple body systems. The name CHARGE is an acronym derived from the most common features of the condition:
CHARGE meaning in Oncology in Medical
CHARGE mostly used in an acronym Oncology in Category Medical that means Coloboma of the eye & central nervous system anomalies, Heart defects, Atresia of the choanae, Retardation of growth and/or development, Genital and/or urinary defects
Shorthand: CHARGE,
Full Form: Coloboma of the eye & central nervous system anomalies, Heart defects, Atresia of the choanae, Retardation of growth and/or development, Genital and/or urinary defects
For more information of "Coloboma of the eye & central nervous system anomalies, Heart defects, Atresia of the choanae, Retardation of growth and/or development, Genital and/or urinary defects", see the section below.
Coloboma of the Eye & Central Nervous System Anomalies
- Coloboma: A birth defect involving a gap or hole in the eye's structure.
- Central Nervous System Anomalies: Structural or functional abnormalities in the brain and spinal cord.
Heart Defects
- Various congenital heart defects, ranging from mild to severe.
Atresia of the Choanae
- Blockage of the nasal passages.
Retardation of Growth and/or Development
- Physical and/or mental developmental delays.
Genital and/or Urinary Defects
- Abnormalities in the reproductive or urinary systems.
Cause
The exact cause of CHARGE syndrome is unknown, but it is believed to be caused by mutations in several genes involved in early embryonic development.
Symptoms
In addition to the core features mentioned above, individuals with CHARGE syndrome may experience a wide range of other symptoms, including:
- Facial dysmorphism (unusual facial features)
- Hearing loss
- Feeding difficulties
- Speech delay
- Behavioral problems
- Vision problems
- Kidney anomalies
- Skeletal abnormalities
Diagnosis
CHARGE syndrome is typically diagnosed based on a combination of clinical features, family history, and genetic testing. Genetic testing can identify mutations in genes associated with the condition.
Treatment
Treatment for CHARGE syndrome is individualized and focuses on managing the specific symptoms and complications of the disorder. This may include:
- Surgical correction of heart defects
- Hearing aids or cochlear implants
- Speech therapy
- Physical therapy
- Occupational therapy
- Special education services
Final Words: CHARGE syndrome is a complex genetic disorder with a wide range of symptoms. Early diagnosis and intervention are crucial for improving outcomes and optimizing the quality of life for individuals affected by this condition.