What does SPRINT mean in PREVENTION
SPRINT stands for Secondary Prevention Reinfarction Israeli Nifedipine Trial. It is an international study that focused on preventing secondary heart attacks in individuals with previous heart attack history. The trial was a double-blind randomized controlled trial involving more than 5000 patients from around the world who had sustained a prior myocardial infarction (MI) or acute coronary syndrome (ACS). The study took place between 1985 and 1992 and compared two treatment regimens: nifedipine versus placebo control group.
SPRINT meaning in Prevention in Medical
SPRINT mostly used in an acronym Prevention in Category Medical that means Secondary Prevention Reinfarction Israeli Nifedipine Trial
Shorthand: SPRINT,
Full Form: Secondary Prevention Reinfarction Israeli Nifedipine Trial
For more information of "Secondary Prevention Reinfarction Israeli Nifedipine Trial", see the section below.
» Medical » Prevention
What Does SPRINT Stand For?
Purpose of the Study:The primary purpose of this trial was to examine whether nifedipine monotherapy reduces mortality and major cardiac events such as a second MI or other activity within one year of enrollment into the trial. There were four secondary objectives, including cumulative mortality over time, hospitalization due to cardiovascular cause, angina episodes requiring drugs, and electrocardiographic changes all linked to changes in left ventricular function.
Results of the Study:The results of this trial showed that those assigned nifedipine monotherapy had reduced risk for mortality by 26%, fewer minor cardiac events by 8%, fewer angina pectoris episodes requiring drugs by 22%, loweredO rate of hospitalizations due to cardiovascular causes by 28 %, improved left ventricular ejection fraction(LVEF), and better qualityof life compared to the control group.Based on these findings, it was concluded that nifedipine monotherapy was beneficial for those with prior MI or ACS history in reducing their risk for mortality as well as other cardiac events over one year’s time frame. These results suggest important benefits associated with early diagnosis and timely intervention following an MI or ACS event utilizing nifedipine monotherapy when appropriate.
Essential Questions and Answers on Secondary Prevention Reinfarction Israeli Nifedipine Trial in "MEDICAL»PREVENTION"
What is the SPRINT trial?
The SPRINT trial (Secondary Prevention Reinfarction Israeli Nifedipine Trial) was designed to evaluate the efficacy and safety of nifedipine in adults with a history of myocardial infarction or unstable angina.
Does the SPRINT trial include any specific research objectives?
Yes, the primary objectives of the study are to compare mortality and morbidity rates between patients taking nifedipine and those taking placebo. In addition, secondary objectives include evaluating changes in systolic blood pressure and cholesterol levels, as well as exploring other factors associated with cardiovascular health outcomes.
How long does the SPRINT trial typically last?
The duration of the trial can vary depending on individual participant health status. Generally, participants are followed for a period of up to five years.
Who is eligible to participate in the SPRINT trial?
Eligibility criteria for participating in this clinical trial includes but is not limited to being 45 years or older, having a documented history of myocardial infarction or unstable angina and meeting all other necessary medical criteria determined by the investigator.
Are there any risks associated with participating in the SPRINT trial?
As with all clinical trials there are some potential risks associated with participation. Risks may include side effects related to study medications, such as nausea, dizziness or gastrointestinal upset. Your study doctor can discuss these potential risks further before you decide whether to participate in this clinical trial.
What type of monitoring will I have during the SPRINT trial?
All participants enrolled in this clinical trial will receive regular monitoring from their study doctor throughout their participation. This monitoring will generally include physical examinations and laboratory tests such as blood tests, electrocardiograms and echocardiograms.
Are there any costs associated with participating in the SPRINT Trial?
No, participation in this clinical trial does not incur any out-of-pocket expenses for participants. All costs related to medications, laboratory tests and procedures related to monitoring your health status during this clinical are covered by study sponsors.
Is it possible for me to leave early from the SPRINT Trial?
Yes, you may choose at any time during your participation to discontinue treatment or even withdraw completely from this clinical trial without consequence.
Will I be compensated if I volunteer for the SPIRNT Trial?
Yes, compensation may be available on completion of your involvement depending on eligibility requirements set out by sponsors conducting research involving human participants.
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